Polynucleotide (Salmon Sperm) – Natural Skin Regeneration at the Cellular Level
Tired-looking skin, fine lines, loss of elasticity – sometimes your face doesn’t reflect how vibrant you feel. And perhaps you’re not looking for “more volume” or “smooth contours”, but for true regeneration. From within. At a cellular level.
This is precisely where polynucleotide treatment (also known as salmon sperm therapy) comes in. At BONITAS, we offer you a revolutionary method of skin rejuvenation that doesn’t use artificial fillers – but sustainably tightens, hydrates, and rebuilds your skin.
At a glance: The polynucleotide treatment regenerates the skin at a cellular level and is suitable for the eye area, the neck and sensitive zones.
- Treatment time: 20–30 minutes
- Material: DNA fragments (from salmon roe, biocompatible)
- Sessions: 3–4 at intervals of 2–3 weeks
- Onset of effect: gradual after 4–6 weeks
- Duration of effect: 6–9 months, maintenance recommended
- Prices: in our price overview
What are Polynucleotides (Salmon Sperm)?
Polynucleotides are natural DNA fragments, obtained from purified salmon sperm. They are almost identical to human DNA and have high biological compatibility.
Their effect:
Unlike fillers, polynucleotides do not directly plump up, but long-term improve skin structure – from the inside out.
Who is the treatment suitable for?
Polynucleotides are ideal for anyone looking for a natural, subtle, and regenerative anti-aging treatment – without adding volume, but with visible vitality.
How does salmon sperm therapy affect your skin?
Action
Results
The skin is sustainably rebuilt, not just concealed – a true game-changer in biostimulation.
Treatment process at BONITAS
For optimal results, we recommend a course of 2–3 sessions spaced 2–4 weeks apart, followed by refreshers every 4–6 months.
Results & Benefits of Polynucleotide Therapy
The result is not a “mask”, but visibly rejuvenated, vital skin – with substance.
Why BONITAS?
BONITAS stands for natural aesthetics – without overcorrection, but with profound effect.
Frequently asked questions (FAQ)
If you are considering medical aesthetic treatment, schedule your consultation for an honest assessment tailored to your needs.
Scientific References
- Lampridou S, Bassett S et al. „The Effectiveness of Polynucleotides in Esthetic Medicine: A Systematic Review.” Journal of Cosmetic Dermatology. 2025. PubMed PMID 39645667
- Marques C, Porcello A et al. „From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions and Clinical Applications.” Biomolecules. 2025. PubMed PMID 39858543
- Lee KWA et al. „Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness.” Int J Mol Sci. 2024. PubMed PMID 39125793
Medically reviewed and written by Alejandro MartĂ
Specialist in Plastic and Aesthetic Surgery 🇩🇪 🇪🇸 · Belegarzt (admitting privileges)
With more than 1,000 plastic and aesthetic treatments performed, both surgical and minimally invasive. Comes from a family with a long tradition in Plastic and Aesthetic Surgery.
Last reviewed: May 2026